TGF-β Signaling Cooperates with AT Motif-Binding Factor-1 for Repression of the α-Fetoprotein Promoter
Figure 4
Importance of both distal and proximal AT-motifs for TGF-β-mediated repression of the AFP promoter. (a) Schematic presentation of CMV Luc conjugated with distal and proximal AT-motifs. (b) HepG2 cells were transfected with each reporter (200 ng) and then stimulated with 5 ng/mL TGF-β.
