Epidemiology Research International

Research Article

Factors Associated with a Poor Treatment Outcome among Children Treated for Malaria in Ibadan, Southwest Nigeria

Multivariate analysis of factors associated with poor treatment outcome.


	Odds ratio	95% C.I	value

Sociodemographic characteristics
Age group
<12	5.99	1.15–31.15	0.033*
12–23	3.05	0.62–14.88	0.169
24–35	2.54	0.51–12.65	0.254
36–47	3.02	0.62–14.80	0.174
48–59	1
≥60	1.08	0.16–6.85	0.939
Mother’s highest level of education
No formal	0.000	0.000	0.997
Primary	1.11	0.19–6.57	0.905
Secondary	1.19	0.23–6.11	0.835
Tertiary	1
Father’s highest level of education
No formal	0.000	0.000	0.998
Primary	1.62	0.31–8.39	0.565
Secondary	2.0	0.48–8.35	0.342
Tertiary	1

Illness history given by caregiver
Any drug used prior to presentation
Yes	1
No	1.43	0.29–6.93	0.657
Use of PCM prior to presentation
Yes	1
No	1.31	0.27–6.44	0.738
Symptoms prior to presentation
Rigors
Yes	1
No	1.51	0.57–4.03	0.409
Loss of appetite
Yes	1
No	1.70	0.78–3.70	0.180
Vomiting
Yes	1
No	0.64	0.31–1.32	0.226
Jaundice
Yes	1.26	0.27–5.87	0.767
No	1
Pallor
Yes	1
No	1.58	0.60–4.13	0.353
Loss of consciousness
Yes	4.55	1.72–12.08	0.002*
No	1
Convulsion
Yes	1.61	0.66–3.94	0.296
No	1

Clinical examination findings
Pallor
Yes	2.54	0.90–7.16	0.078
No	1
Jaundice
Yes	2.05	0.55–7.64	0.284
No	1
Patients’ temperature
Febrile	1.89	0.77–4.63	0.163
Normal	1
Sub-normal	11.52	1.07–123.64	0.044*
Hypothermia	—
Hepatomegaly
Yes	1.17	0.51–2.68	0.709
No	1
Splenomegaly
Yes	1.95	0.82–4.62	0.129
No	1
Respiratory distress
Yes
No
Anaemia
Severe	2.62	0.67–10.18	0.165
Mild	0.87	0.21–3.72	0.854
Moderate	1.50	0.45–5.01	0.507
No anaemia	1

Statistically significant.