Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression
Table 6
Gene ontology analysis for enrichment of biological function with 2 mM EMS treatment.
Biological function
valuea
Number of genesb
Diseases and disorders
Developmental disorder
177
Skeletal and muscular disorders
66
Infectious disease
170
Connective tissue disorder
40
Cardiovascular disease
43
Molecular and cellular functions
Cellular movement
204
Amino acid metabolism
78
Small molecule biochemistry
183
Cellular assembly and organization
179
Cellular function and maintenance
189
Physiological system development and function
Tissue morphology
209
Organismal survival
187
Embryonic development
221
Organismal development
284
Organ morphology
143
Derived from the likelihood of observing the degree of enrichment in a gene set of a given size by chance alone. A maximum false discovery rate of 5% was accepted in this analysis. Classified as being differentially expressed that relate to the specified function category; a gene may be present in more than one category.