Research Article
Examining Provincial HPV Vaccination Schemes in Canada: Should We Standardise the Grade of Vaccination or the Number of Doses?
Table 2
List of parameters and state variables.
| Parameter | Description | Range | Sample value | Reference |
| | Unvaccinated children in grade | (State variable) | | | | Unvaccinated adult women | (State variable) | | | | Vaccinated children in grade | (State variable) | | | | Vaccinated adult women | (State variable) | | | | Uninfected adult women | (State variable) | | | | Infected adult women | (State variable) | | | | Uninfected men | (State variable) | | | | Infected men | (State variable) | | | , | Birth rate for women, men | 50–100 people | 100 | [4] | | Mortality rate for children | 1/50–1/90 year−1 | 1/90 | 1/avg. time in compartment | | Leaving rate for adults | 1/12–1/8 year−1 | 1/10 | 1/avg. time in compartment | | Vaccine efficacy in female children | 93.3–99.8% 2 doses | 0.97 | [3] | 93.3–99.8% 3 doses | 0.99 | [3] | | Vaccine efficacy in adult women | 50.2–96.3% 2 doses | 0.809 | [3, 5, 21–24] | 71.1–87.7% 3 doses | 0.841 | [3, 5, 21–24] | , where | Proportion of children vaccinated within the corresponding grade | 0–100% | | [16, 17, 19, 20] | | Proportion of previously unvaccinated adult women vaccinated | 0–100% | | [16, 17, 19, 20] | | Transmission of infection of a woman by an infected man | 0.01–2 year−1 | 0.77 | [2] | | Transmission of infection of a man by an infected woman | 0.01–2 year−1 | 0.77 | [2] | | Proportion of infected girls at age 15 unvaccinated, vaccinated | 0–30% | 10% | [25] | | Probability of protection against all targeted types | 0.3–1 | 0.44 | [23] | | Recovery rate for unvaccinated women, vaccinated women, men | 1/2–4/3 year−1 | 2/3 | [26, 27] | | Attenuation constant | 0–0.3 year−1 | | [4] | | Maximal possible rate of adult vaccination | 0–0.2 | 0.1 | [4] | | Rate at which unvaccinated women are vaccinated | | | [4] | | Waning rate | 0.2–1 year−1 2 doses | 0.5 | [28] | 0.1–0.5 year−1 3 doses | 0.333 | [28] |
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