Research Article

Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis

Table 2

List of phospholipids in THP-1 cells infected with either H37Ra or H37Rv by shotgun lipidomics approach.

Name of lipidsH37RaH37Rv

PG0.410.63
PA0.300.78
PI0.110.18
PIP20.895.6
PE0.280.80
PS0.740.69
PC1.292.22
SM5.212.14
PC/PE6.792.76

Phosphatidyl glycerol (PG), phosphatidic acid (PA), phosphatidyl inositol (PI), phosphatidyl inositol bisphosphate (PIP2), phosphatidyl ethanolamine (PE), phosphatidyl serine (PS), phosphatidyl choline (PC), and sphingomyelin (SM) were identified confidently. Among them, PC/PE ratio, PIP2, and SM were shown to be differentially altered. Data is representative of the three biological repeats after normalization with control sample.