A Kinetic Model of Whole-Body Glucose Metabolism with Reference to the Domestic Dog (Canis lupus familiaris)
Table 3
Postprandial glucose kinetics parameters in adult Labrador Retrievers fed two different diets (control, CON, or treatment, TRMT). Data are expressed as mean and standard error (flows are expressed as μmol/(min·kg)).
Diet
BW, kg
/dose, %
Experiment A
CON†
30.9 ± 1.6
0.136
0.004 ± 0.000
0.001 ± 0.000
12.5 ± 0.3
34 ± 5
0
35.0 ± 4.7
22 ± 4
16.3 ± 2.2
TRMT†
31.3 ± 1.8
0.136
0.005 ± 0.000
0.001 ± 0.000
10.1 ± 1.1
29 ± 2
0
30.5 ± 2.0
20 ± 1
14.1 ± 1.0
CON‡
30.9 ± 1.6
0.136
0.003 ± 0.001
0.002 ± 0.001
6.4 ± 0.6
78 ± 34
0
80.6 ± 34.9
72 ± 33
37.5 ± 16.3
TRMT‡
31.3 ± 1.8
0.136
0.003 ± 0.001
0.003 ± 0.000
5.7 ± 0.4
48 ± 10
0
49.3 ± 10.6
42 ± 10
22.9 ± 5.0
Experiment B
CON
27.4 ± 0.7
0.136
0.001 ± 0.000
0.001 ± 0.000
61 ± 18
224 ± 56
0
225 ± 56
163 ± 40
35.6 ± 7.1
TRMT
27.6 ± 0.7
0.136
0.001 ± 0.000
0.001 ± 0.000
37 ± 7
152 ± 30
0
153 ± 30
116 ± 23
35.2 ± 5.7
Dogs were fed 14 g/meal glucose. †Experimental enrichment values (last sampling time point). ‡Extrapolated steady state enrichments. Dogs were fed 23 g/meal glucose. Crude estimate of glucose absorption, based on diets providing 760 g glucose/kg fed in 25 min intervals.
