Advances in Pharmaceutics

Research Article

Formulation, Optimization, and Characterization of Repaglinide Loaded Nanocrystal for Diabetes Therapy

Table 5

Stability study of optimized formulation.
Stability studyParticle size (nm)Zeta potential (mV)
(Mean ± SD)(Mean ± SD)
Starting formulation187 ± 5.09–29.4 ± 1.00 
After 3 months  
 5°C ± 3°C (refrigerator)190 ± 2.21–28.1 ± 0.22 
 30°C ± 2°C/65% ± 5% RH195.4 ± 1.89−25.5 ± 1.2
 (Ambient conditions)
 40°C ± 2°C/75% ± 5% RH201.8 ± 3.1−22.2 ± 1.8
 (Stability Chamber)