Structural Differences in KIR3DL1 and LILRB1 Interaction with HLA-B and the Loading Peptide Polymorphisms: In Silico Evidences
Table 1
List of KIR3DL1 alleles selected for immune-informatics approach. Alleles were selected depending on amino acid polymorphisms with respect to the reference allele KIR3DL1001 and allele frequency in general population [36, 37].
Expression
KIR3DL1 alleles
KIR3DL1 polymorphic amino acid position (7–292)
47
54
58
92
182
283
High
KIR3DL1001
I
I
S
V
P
W
KIR3DL1009
V
I
G
M
P
W
KIR3DL1015#
V
L
S
V
P
W
Low
KIR3DL1007#
V
L
S
V
P
W
KIR3DL1005
I
I
S
V
S
L
007 and 015 share the same amino acid polymorphisms and have been analyzed together.
