Leukemia Research and Treatment

Research Article

Isochromosome 17q in Chronic Lymphocytic Leukemia

Table 2

Summary of MLPA and iFISH results of IKZF3- and UNC13D-gene specific probes and subtelomeric probes for chromosome 17 in 10 CLL cases with TP53 deletion in the first group.
Case numberTP53  %]UNC13D  %]IKZF3  %]iFISH  %]
MLPAiFISHMLPAiFISHMLPAiFISHSubtel. pterSubtel. qter
1dd 95]aa 90]aa 90]d 90]a 90]
2dd 40]aa 40]aa 40]d 40]a 40]
3dd 40]na 25]na 25]d 25]a 25]
4dd 36]nnnnnn
5dd 21]nnnnnn
6dd 89]nnnnnn
7dd 19]nnnnnn
8dd 86]nnnnnn
9dd 77]nnnnnn
10nd 11,5]nnnnnn
11 to 85nnnn.a.nn.a.n.a.n.a.
n = no aberration, d = deletion, a = amplification, n.a. = not tested, and = percentage of cells with aberration.