Molecular Biology International

Research Article

FOXO3a Gene Polymorphism Associated with Asthma in Indian Population

Table 4

The genotype and allele frequencies for asthmatic patients and control subjects of rs13217795 of FOXO3a gene.
  Frequencies valueDegrees of freedom
Asthmatic patients Healthy controls
()()
Genotype CC 11 (9.65%) 72 (50.70%) <0.0001 2
CT 44 (38.6%)52 (36.61%)
TT59 (51.75%)18(12.67%)
Allele C 66 (28.95%) 196 (69.01%) <0.0001 1
T162 (71.05%)88 (30.99%)
Chi-square test ().
Odds ratio from genotypic frequency (keeping CC as baseline):
CT—5.54; 95% confidence interval = 2.48 to 12.62.
TT—21.45; 95% confidence interval = 8.78 to 53.84.
From allelic frequency:
odds ratio = 5.47; 95% confidence interval = 3.67 to 8.16.