Dependence of survival of the experimental and control group of mice on age (months). Experimental group (dashed line) was transplanted without additional conditioning with bone marrow cells from young donors starting with recipient age of 6–8 months (syngeneic transplantation (a)–(d)) or 13-14 months (allogeneic transplantation (e)), regularly every three months. Solid line: control group (no transplantation). (a) First group (eGFP C57Bl/6 female mice for which the additional inbreeding was carried out to approximate genomes of donor and recipient): syngeneic transplantation to eGFP⁻ mice from eGFP⁺ mice. Mean lifespan (MLS) was months (experiment, ) and months (control, ) (34% excess of control; ). (b) Second group (eGFP C57Bl/6 female mice): syngeneic transplantation to eGFP⁻ mice from eGFP⁺ mice. MLS was months (experiment, ) and months (control, ) (19% excess of control; ). (c) First and second groups together: MLS for the experimental group was months and for the control – months (25% excess of control; ). (d) Third group: syngeneic transplantation to eGFP⁻ C57Bl/6 mice (males) from eGFP⁺ C57Bl/6 mice (females and males); MLS was months (experiment, ) and months (control, ) (10% excess of control; ). (e) Allogeneic transplantation to BALB mice (females) from eGFP⁺ C57Bl/6 mice (females and males): MLS was months (experiment, ) and months (control, ) (; significant difference was not observed in survival dynamics of experimental and control groups of BALB mice).