Advances in Pharmaceutics

Research Article

Formulation Development of Mouth Dissolving Film of Etoricoxib for Pain Management

Table 1

Formulation of etoricoxib MDF.
Batch codeEF-1EF-2
S. numberIngredientsQuantity/film
1.Etoricoxib-beta-cyclodextrin complex426.7 m886.4 m
2.Hypromellose (hydroxypropyl methyl cellulose 15 cPs)150 mg150 mg
3.Sucralose50 mg50 mg
4.Mixed fruit flavour 1486910.025 mL0.025 mL
5.Bitter masking flavour 6897960.025 mL0.025 mL
6.Glycerin65 mg65 mg
7.Distilled water 5 mL5 mL
Quantity equivalent to 30 mg of etoricoxib in single dose MDF. EF-1-MDF with beta-cyclodextrin inclusion complex (1 : 1 g ratio). EF-2-MDF with beta-cyclodextrin inclusion complex (1 : 1 molar ratio).