Research Article

Molecular Docking Study Characterization of Rare Flavonoids at the Nac-Binding Site of the First Bromodomain of BRD4 (BRD4 BD1)

Figure 10

Naringenin triacetate. C2 branched 4-acetyloxy cyclohexyl moiety on its perpendicular axis has its steric interactions in three directions via Pro82, Leu92, and Val87. On the other side Phe83 directly interacts with carbonyl oxygen from 4-acetyl of cyclohexyl moiety. Image generated using Accelrys’ discovery studio 4.0 [25].