Molecular Docking Study Characterization of Rare Flavonoids at the Nac-Binding Site of the First Bromodomain of BRD4 (BRD4 BD1)

<div>5-Hydroxy-7-acetoxy-8-methoxy flavone. The steric interactions with Pro82, Phe83, Tyr97, Met132, Met105, and Asn135 enhanced the affinity of binding. Tyr 97 was found to show hydrophobic interaction abundance with 5-hydroxyl-7-acetoxy-8-methoxy flavone.</div>

Journal of Cancer Research

fig13

Figure 13

Figure 13: Molecular Docking Study Characterization of Rare Flavonoids at the Nac-Binding Site of the First Bromodomain of BRD4 (BRD4 BD1) 