Research Article

Molecular Docking Study Characterization of Rare Flavonoids at the Nac-Binding Site of the First Bromodomain of BRD4 (BRD4 BD1)

Figure 2

Secondary structure of bromodomain BD1-BRD4 with water molecules showing N-terminus, α-Z helix, α-A helix, ZA loop, AB loop, α-B helix, BC loop, and α-C helix. Adjacent image with white arrows below shows a secondary structure and surface diagram which in turn emphasizes a circled area of hydrophobic sites. Diagram of secondary structure generated using Accelrys’ discovery studio 4.0 [25].