Research Article
Molecular Docking Study Characterization of Rare Flavonoids at the Nac-Binding Site of the First Bromodomain of BRD4 (BRD4 BD1)
Figure 9
3-O-Acetylpinobanksin. Hydrophobic interactions of C2 substituted (2R, 3R)-2-cyclo-hexyl moiety have their unidirectional hydrophobic interactions from Pro82 and a bidirectional force of attraction with Leu92 and Val87 is projected. Benzopyrone nucleus under the influence of Val87 holds a hydrophobic interaction with Ile146 and Cys136. Image is generated using Accelrys’ discovery studio 4.0 [25].