Review Article
Malignant Transformation Rate in Patients Presenting Oral Epithelial Dysplasia: Systematic Review and Meta-Analysis
Table 2
Oral epithelial dysplasia (OED) count and malignant transformation rate (MTR).
| | First author | Year | Oral epithelial dysplasia | Malignant transformation | Malignant transformation rate | | Total | Mild | Mod. | Sev. | Total | Mild | Mod. | Sev. | Total | Mild | Mod. | Sev. |
| | Bánóczy [13] | 1976 | 68 | 13 | 43 | 12 | 9 | 1 | 3 | 5 | 13.2% | 7.7% | 7.0% | 41.7% | | Mincer [17] | 1972 | 45 | NA | 32 | 13 | 5 | NA | 2 | 3 | 11.1% | NA | 6.3% | 23.1% | | Gupta [7] | 1980 | 90 | NA | NA | NA | 6 | NA | NA | NA | 6.7% | NA | NA | NA | | Lumerman [18] | 1995 | 43 | 19 | 18 | 6 | 7 | 3 | 3 | 1 | 16.3% | 15.8% | 16.7% | 16.7% | | Cowan [12] | 2001 | 165 | NA | NA | NA | 24 | NA | NA | NA | 14.6% | NA | NA | NA | | Holmstrup [11] | 2006 | 82 | 42 | 26 | 14 | 8 | 5 | 2 | 1 | 9.8% | 11.9% | 7.7% | 7.1% | | Hsue [8] | 2007 | 166 | NA | NA | NA | 8 | NA | NA | NA | 4.8% | NA | NA | NA | | Ho [9] | 2009 | 33 | NA | NA | NA | 8 | NA | NA | NA | 24.2% | NA | NA | NA | | Arduino [16] | 2009 | 207 | 135 | 50 | 22 | 15 | 4 | 2 | 9 | 7.3% | 3.0% | 4.0% | 43.0% | | Bradley [21] | 2010 | 1434 | 959 | 326 | 149 | 139 | 47 | 43 | 49 | 9.7% | 4.9% | 13.2% | 32.9% | | Liu [10] | 2011 | 138 | 92 | NA | 46 | 37 | 17 | NA | 20 | 26.8% | 18.5% | NA | 43.5% | | Warnakulasuriya [15] | 2011 | 204 | 104 | 70 | 30 | 24 | 5 | 11 | 8 | 11.8% | 4.8% | 15.7% | 26.7% | | Ho [14] | 2012 | 91 | 40 | 31 | 20 | 23 | 8 | 11 | 11 | 25.3% | 20.0% | 35.5% | 55.0% | | Zhang [22] | 2012 | 296 | 127 | 135 | 34 | 41 | 16 | 19 | 6 | 13.9% | 12.6% | 14.1% | 17.7% | | Sperandio [19] | 2013 | 201 | 103 | 69 | 29 | 17 | 4 | 7 | 6 | 8.5% | 3.9% | 10.1% | 20.7% | | Dost [20] | 2014 | 368 | 221 | 85 | 55 | 26 | 9 | 6 | 1 | 7.1% | 4.1% | 7.1% | 1.8% |
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NA: not available.
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