Research Article
Smoking and Heberden Nodes: Analysis of Data from the Osteoarthritis Initiative
Table 3
Odds ratios and 95% confidence intervals from logistic regression on Heberden’s nodes, Osteoarthritis Initiative data.
| | | Odds ratio
confidence interval | value |
| | Unadjusted | | | | Smoking | | | | Yes, current | 0.61 0.46, 0.81 | .0007 | | Never (<5 packs/lifetime) | Referent | |
| | Adjusted model | | | | Smoking | | .2488 | | Yes, current | 0.83 0.60, 1.14 | | | Never (<5 packs/lifetime) | Referent | | | Sex | | <.0001 | | Female | 3.65 2.98, 4.48 | | | Male | Referent | | | Race/ethnicity | | | | Non-Hispanic White | Referent | | | Non-Hispanic Black | 0.38 0.29, 0.49 | <.0001 | | Hispanic/other | 1.12 0.61, 2.08 | .7094 | | Age | | | | 45 to <56 | Referent | | | ≥56 to <66 | 1.97 1.57, 2.48 | <.0001 | | ≥66 | 2.81 2.22, 3.55 | <.0001 | | Body mass index | | | | <25 (normal weight) | Referent | | | ≥25 to <30 (overweight) | 1.02 0.81, 1.27 | .8988 | | ≥30 (obese) | 0.72 0.57, 0.93 | .0105 | | Right knee radiographic evaluation | | | | Normal | Referent | | | Possible osteoarthritis | 1.16 0.89, 1.52 | .2722 | | Mild | 1.22 0.90, 1.65 | .1984 | | Moderate | 1.16 0.86, 1.58 | .3359 | | Severe | 1.17 0.74, 1.84 | .4998 | | Family history of osteoarthritis | | | | Yes | 1.24 0.92, 1.69 | .1625 | | No | Referent | | | Education | | | | High school or less | 1.16 0.91, 1.50 | .2372 | | More than high school | Referent | | | MOS SF-12 quartiles | | | | Quartile 1 | 1.53 1.18, 1.98 | .0015 | | Quartile 2 | 1.40 1.09, 1.80 | .0096 | | Quartile 3 | 1.28 0.99, 1.64 | .0577 | | Quartile 4 | Referent | |
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Medical Outcomes Study Short Form-12 version 2 physical summary scale.
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