Research Article

Effects of Swimming Exercise on Limbic and Motor Cortex Neurogenesis in the Kainate-Lesion Model of Temporal Lobe Epilepsy

Figure 3

Effects of 30 d swimming exercise on morphometric cell counts in dentate gyrus of hippocampus and basolateral nuclei of amygdala. Morphometric cell counts of the surviving neurons in groups of 4-month-old male Wistar rats exposed to the following conditions: normal control (NC), normal control followed by swimming exercise (NC+EX), sham-operated control followed by swimming exercise (SC+EX), and kainic acid-induced lesioning and seizures (LO) followed by swimming exercise (L+EX) treatments. (a and b) Dentate gyrus of hippocampus. (c and d) Basolateral nuclei of amygdala. (a and c) Effects of immediate (1 d postgrouping for controls, 1 d postictal period for lesioned rats) exposure to the swimming exercise. (b and d) Effects of delayed (60 d postgrouping for controls, 60 d postictal period for lesioned rats) exposure to the swimming exercise in dentate gyrus and basolateral amygdala, respectively. Bars represent number of surviving neurons expressed in means ± standard errors. Intergroup differences significant at and . -values for (a–d) 307.1, 972.2, 112.6, and 173.7, respectively.
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