Functional performance and neuromuscular function. (a) Individual change in total scores of the revised ALS functional rating scale (ALSFRS-R). Changes in functional performance in (b) chair rise and (c) timed up and go (TUG) during control and training periods. Note that one participant was unable to perform chair rise at Pre and Post as well as TUG at Post; thus these data are excluded. Change in maximal voluntary muscle strength (MVC) of (d) knee extensors, (e) handgrip, and (f) plantar flexor during the control and training period. (g) Change in explosive leg extension power. (h) Voluntary muscle activation measured by doublet twitch stimulations. Dots represent individual values of change from BL to Pre (control period) and from Pre to Post (training period).