International Scholarly Research Notices

Research Article

Anorectal Motility and Sensation Abnormalities and Its Correlation with Anorectal Symptoms in Patients with Systemic Sclerosis: A Preliminary Study

Table 4

Anorectal measurements for the SSc patients and the controls.
VariablesSSc patientsControlsP value
Manometry
 Max. anal resting pressure (mmHg) 2 7 . 5 ± 5 4 8 . 8 ± 4 .002
 Max. squeeze pressure (mmHg) 7 1 . 8 ± 1 4 9 7 . 5 ± 5 .05
 % increase in anal sphincter pressure during squeeze (mmHg) 3 2 . 3 ± 5 5 0 . 6 ± 5 .01
 Maximum intrarectal pressure (mmHg) 4 5 . 5 ± 6 6 7 . 5 ± 5 .01
 Residual anal sphincter pressure during straining (mmHg) 1 9 . 6 ± 8 2 9 . 5 ± 6 .1
 Least volume to induce RAIR (mL) 2 5 . 0 ± 6 1 7 . 5 ± 3 .13
 Threshold for 1st sensation (mL) 2 3 . 8 ± 5 3 8 . 8 ± 6 .03
 Threshold for Urge to defecate (mL) 7 3 . 8 ± 1 3 9 3 . 8 ± 7 .04
 Maximum tolerable volume (mL) 1 0 8 . 8 ± 1 4 1 5 6 . 3 ± 1 3 .01
Compliance
 Kappa (instantaneous slope of the curve) 1 . 1 ± 0 1 . 2 ± 0 .4
 Beta (overall shape of the curve) 2 6 . 4 ± 4 3 4 . 8 ± 3 .05
  𝑃 1 / 2 (half-max volume on pressure-volume curve - mmHg) 1 6 . 8 ± 2 2 2 . 0 ± 2 .03
  𝑃 m a x (maximum tolerated pressure - mmHg) 3 3 . 1 ± 2 4 2 . 1 ± 4 .05