Mode of Action of Lactoperoxidase as Related to Its Antimicrobial Activity: A Review
Figure 9
Biological activity of hypoiodite or iodine on bacteria. Irreversible inhibition is observed and could be linked to (i) oxidation of thiol groups, NAD(P)H, and thioether groups, (ii) high reactivity of HOI/I2 against thiol and reduced nicotinamide nucleotides, and (iii) the incorporation of iodide in tyrosine residue of protein (iodination of protein). HOI/OIā: acid or basic form of hypoiodite and I2: iodine.
