Review Article
Genetic Markers Used for Risk Stratification in Multiple Myeloma
Table 1
Abnormalities associated with outcome in MM and techniques used for detection.
| Abnormalities | Outcome | Test |
| t(4;14)(p16;q32) | Poor | FISH* | t(14;16)(q32;q23) | Poor | FISH | t(6;14)(p21;q32) | Good? | FISH | t(11;14)(q13;q32) | Good/neutral | FISH | Deletion 17p13 | Poor | FISH | Deletion 13 | Poor | Convenlional cytogenetics | Chromosome 1 abnormalities | Poor | FISH | Hyperdiploidy | Good | FISH or FCM** | (if not associated with deletion 17p13) |
|
|
*Fluorescence in situ hybridization (FISH). **Flow cytometry.
|