Lack of Association between Variant rs7916697 in ATOH7 and Primary Open Angle Glaucoma in a Saudi Cohort

Table 2

Association analysis of allele frequency and genotype distribution for SNP rs7916697 in POAG patients and controls.

SNP (Gene)	rs7916697 (ATOH7)
	Controls; (n = 171); No. ()	POAG; (n = 186); No. ()	Odds ratio	95 confidence interval	p value^a
Allelic analysis
G	219 (64.0)	227 (61.0)	1	Reference	-
A^∗	123 (36.0)	145 (39.0)	0.88	0.65 – 1.19	0.406
HWE P	0.968	0.936	-	-	-
Genotype and Model analysis
G/G	70 (40.9)	69 (37.1)	1	Reference	-
G/A	79 (46.2)	89 (47.8)	0.87	0.55 – 1.37	0.560
A/A	22 (12.8)	28 (15.0)	0.77	0.40 – 1.48	0.438
Additive	-	-	-	-	0.707^§
Dominant	-	-	0.85	0.55 – 1.30	0.458
Recessive	-	-	0.83	0.45 – 1.52	0.554

Chi² test. ^∗Risk variant. HWE P, Hardy-Weinberg equilibrium p value. ^§Fisher exact test.