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Polymer | Antineoplastic agents/action | Cancer | Route of administration | Reference |
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MPEG-b-(PCL-ran-PLLA) diblock copolymer (MCL) | 5-Fluorouracil | Melanoma in vivo mice model tumor | Subcutaneously injected drug delivery system | Seo and coworkers [33] |
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Hydroxypropyl-β-cyclodextrin supported in in-situ-forming hydrogels with poloxamers 407 and 188 | Curcumin/antioxidant, anti-inflammatory, antiproliferative and antiangiogenic activities | In vitro melanoma model in cell lines | Transdermal drug delivery system | Sun and coworkers [34] |
|
Pluronic F127 | Ibuprofen/nonsteroidal anti-inflammatory | In vitro melanoma model in cell lines | Topical/transdermal drug delivery system | Marques and MacNeil [35] |
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Hydrazone cross-linked sericin/dextran | Doxorubicin | In vivo melanoma model in male mice | Subcutaneously injected drug delivery system | Liu and coworkers [36] |
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Glycol chitosan benzaldehyde capped poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (GC-OHC-PEO-PPO-PEO-CHO) | Paclitaxel and doxorubicin (combination therapy) | In vivo melanoma model in male mice | Subcutaneously injected drug delivery system | Zhao and coworkers [37] |
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Poly(2-hydroxypropyl acrylate/itaconic acid) (P(HPA/IA)) | Ni(II) complex with oxaprozin/antiproliferative activity | In vitro melanoma cancer cell lines | Topical/transdermal drug delivery system | Babić and Coworkers [38] |
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Nanohydrogels (NHs) based on cholesterol-graft-hyaluronic acid | Bovine serum amine oxidase (BSAO) | In vitro melanoma cancer cell lines | Topical drug delivery system | Montanari and coworkers [39] |
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Arginate/chitosan | Bovine serum amine oxidase (BSAO) | | Topical drug delivery system | Agostinelli and coworkers [40] |
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Pluronic F127 | AuNPs and DOX | In vivo melanoma model in male mouse | Subcutaneously injected drug delivery system/hyperthermia therapy | Li and coworkers [41] |
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