Review Article

Imagine the Superiority of Dry Powder Inhalers from Carrier Engineering

Table 4

Crystallized lactose based DPI formulations.

DrugMethodKey ingredientsDevice and flow rate% FPFReferences
(l/min)

SSASCLactochem and
acetonewater (85 : 15)
Rotahaler and 60[23]
SSASCEthanolbutanol (20 : 60)-[24]
SSASCEthanolacetone (40 : 40)Aerolizer and 92[25]
SSASCPharmatose 100 M and
ethanolbutanol
Aerolizer and 92-[8]
SSASCPharmatose 100 M and
butanolacetone (80 : 00)
Aerolizer and 92-[26]

ASC: antisolvent crystallization; SS: salbutamol sulphate.