Rate of Drug Coating Dissolution Determines In-Tissue Drug Retention and Durability of Biological Efficacy

<div>Dissolution of solid phase paclitaxel in plasma shown as nonconstrained normalized mean percentage of total solid phase drug solubilized ± SD (a) or remaining solid phase drug in suspension (b) calculated by subtraction from total normalized input drug.</div>

Journal of Drug Delivery

fig1

Figure 1

Figure 1: Rate of Drug Coating Dissolution Determines In-Tissue Drug Retention and Durability of Biological Efficacy 