Nanotechnology-Based Approach in Tuberculosis Treatment

Table 1

TB drugs development in pipeline.

	Discovery	Preclinical development	Clinical development
			Phase 1	Phase 2	Phase 3
Existing drugs redeveloped or repurposed for TB				Linezolid, rifapentine	Gatifloxacin, moxifloxacin
New drugs developed specifically for TB	Nitroimidazole, riminophenazines, translocase-1 inhibitor, InhA inhibitor, GyrB inhibitor, LueRS inhibitor, pyrazinamide analogues, diarylquinoline, spectinamides	CPZEN-45, SQ641, SQ609, DC159a, Q201	AZD5847	Bedaquiline (TMC-207), PA-824, SQ-109, PNU-100480	Delamanid (OPC67683)