Clinical Study

The Use of Lidocaine and Bupivacaine Mix in Adult Safe Male Circumcision: Less Is More

Table 2

Comparing the means of the two groups, 4 : 4 : 2 and 3 : 3 : 4.

Variable 4 : 4 : 2 group 3 : 3 : 4 group value

Age 26 years25 years 0.280
Weight 63 kg 61 kg 0.900
Breakthrough pain (during procedure) 28 0.079
Those with pain at zero minutes (just after procedure)31 0.083
Those with pain at 30 min (after procedure)20 (20%)28 (26%) 0.351
Those with pain at 60 min (after procedure)35 (38%)26 (24%) 0.035
Mean pain score at zero 5 (3–8) 2 0.370
Mean pain scores at 30 min 4 (1–9) 3.4 (1–9) 0.209
Mean pain score at 60 min 3.3 (1–8) 3.5 (1–7) 0.695
LiB related AEs reported 0 0

For the scores at 30 min: those who had a pain score below or equal to 5 (mild pain) were 11/20 and 25/28 for the 4 : 4 : 2 and 3 : 3 : 4 groups, respectively.
For the scores at 60 min: those who had a pain score equal to or below 5 (mild pain) were 23/35 and 19/26 for 4 : 4 : 2 and 3 : 3 : 4 groups, respectively.
Those who registered a pain score of 9 were 2 (<1%), one in each group; all clients that reported pain received additional oral analgesia, and they were not in distress.
All breakthrough pain (during procedure) was classified as mild.