Prevalence of Hypogonadism in a Male Population below 60 Years of Age with Metabolic Syndrome

Table 2

Variables expressed in average normal distribution ± standard deviation analyzed by ANOVA. Nonnormal distribution variables, expressed as median + confidence interval, analyzed by Kruskal-Wallis test.

Testosterone (cut-off < 10.4 nmol/L)	Hypogonadism (18)	No hypogonadism (83)
Age (yr)	45 (31–55)	37 (34–40)	NS
IMC (kg/mt^2)	35 ± 4.5	33 ± 4.7	NS
Waist (cm)	114 ± 11	108 ± 10	NS
Body fat (%)	35.5 ± 4.8	34 ± 4.2	NS
Body lean mass (%)	29 ± 2.6	30 ± 2.5	NS
Visceral fat (%)	18 ± 4.4	15 ± 4.0	0.003
Basal glycemia (mmol/L)	5.49 (4.99–5.71)	5.27 (5.21–5.38)	NS
Postload glycemia (mmol/L)	6.32 ± 1.23	7.10 ± 2.22	NS
Basal insulin (mIU/L)	19.9 (16–32)	15.4 (13–17)	0.01
Postload insulin (mIU/L)	107 (92–218)	127 (97–152)	NS
HOMA	4.2 (3.9–7.27)	3.7 (3.1–3.9)	0.01
QUICKI	0.31 (0.29–0.31)	0.32 (0.31–0.32)	0.02
Cholesterol (mmol/L)	5.30 ± 0.88	5.18 ± 0.98	NS
Cholesterol HDL (mmol/L)	0.89 (0.88–0.98)	0.89 (0-93–1.26)	NS
Triglyceride (mmol/L)	2.40 (1.67–3.46)	2.20 (1.70–2.67)	NS
c free testosterone (nmol/L)	16.3 (12–20)	25 (23–27)	0.001
SHBG (nmol/L)	67 ± 13	96 ± 22	0.000
LH (mU/mL)	3.65 (2.05–4.74)	4.37 (3.81–4.9)	0.04
Estradiol (pmol/L)	89.2 (78.9–106)	106.4 (99–117.4)	0.01
TSH (μIU/mL)	2.4 (1.6–2.88)	2.35 (2.14–2.88)	NS
Prolactin (pmol/L)	432 (282–435)	347 (421–430)	NS