An Electronic Circuit Model of the Interpostsynaptic Functional LINK Designed to Study the Formation of Internal Sensations in the Nervous System

Figure 1

Diagrammatic representation of a synapse at rest and during arrival of an activity. (a) Synapse [A-B] at rest showing the quantal release of neurotransmitters from the presynaptic terminal A resulting in the formation of miniature potentials at the postsynaptic membrane B. The fact that it is difficult to block mEPSP recorded from the neuronal cell body even in experimental conditions indicates that it is likely an evolutionarily highly conserved mechanism. On the right side of the synapse is a graph showing miniature potentials at the postsynapse B at rest (axes are not scaled). (b) A second synapse [C-D] where the arrival of activity at the presynaptic terminal C results in the release of large number of synaptic vesicles resulting in the generation of EPSP at the postsynaptic terminal D. On the right side of the synapse is a graph showing potentials at the postsynapse D at rest (baseline) and during artificial stimulation (one spike) (they are not scaled and only intended to show the difference).

(a)

(b)