Research Article

Pathway-Based Feature Selection Algorithm for Cancer Microarray Data

Table 1

List of publications supporting the first twenty features obtained from BCR data set about their responsibility for cancer.

Gene Supporting Publications Gene Supporting Publications

KCNK2Acute Lymphoblastic Leukemia: [27] ZNF222 Breast cancer: [28]

P2RY2 Human lung epithelial tumor: [29], Non-melanoma skin cancer: [30], Thyroid cancer: [31] SLC2A6 Human Leukemia: [32]

CD163 Breast Cancer: [33], Human colorectal cancer [34] HOXC13 Acute myeloid leukemia: [35, 36]

PCSK6 Breast Cancer: [37], Ovarian cancer: [38] AQP9 Leukemia: [39]

PYY Peptide YY (PYY) is a naturally occurring gut hormone with mostly inhibitory actions on multiple tissue targets [40] KLRC4 KLRC4 is a member of the NKG2 group that are expressed primarily in natural killer (NK) cells [41]

CYP2A13 Lung adenocarcinoma: [42] GRM2 Metastatic Colorectal Carcinoma: [43]

PHOX2B Neuroblastoma: [44] ASCL1 Prostate cancer: [45], Lung cancer: [46]

PKD1 Polycystin-1 induced apoptosis and cell cycle arrest in G0/G1 phase in cancer cells [47]. PKD1 inhibits cancer cells migration and invasion via Wnt signaling pathway in vitro [48]. Gastric cancer: [49] ANGPT4 Gastrointestinal stromal tumor, leiomyoma and schwannoma [50], renal epithelial and clear cell carcinoma [51]

PSMB1 Breast Cancer: [52] RUNX1 Gastric cancer: [53, 54], Ovarian cancer: [55], Classical tumor suppressor gene: [56]

CD1C Prostate cancer: [57] ZNF557Myeloid Leukemia: [58]