Cotranslational Protein Folding and Terminus Hydrophobicity

Figure 4

ALR (dominance of previous contacts) for 90 protein sequences from the PISCES set against (N−C) difference in mean terminus hydrophobicity. The N-terminus and C-terminus of these proteins are the first and last ten residues in their sequences, respectively. Hydrophobicity was assigned using the Kyte-Doolittle, Janin, Cornette, and Eisenberg scales. Note that ALR increases as the difference in mean terminal hydrophobicity increases, for all four scales.