MicroRNA Response Elements-Mediated miRNA-miRNA Interactions in Prostate Cancer

Figure 1

Overview of MRE-mediated miRNA-miRNA network construction. miRNA-miRNA interaction network was constructed by combing miRNA-target networks and expression profiles of both miRNAs and targets. I considered competition between miRNAs for common targets to construct miRNA-miRNA network. miRNAs that target same 3′UTR or MRE and are conditionally dependent on target are anticipated to be functionally associated.