Research Article
Utilization of Boron Compounds for the Modification of Suberoyl Anilide Hydroxamic Acid as Inhibitor of Histone Deacetylase Class II Homo sapiens
Table 8
Carcinogenicity and mutagenicity of the best ligands.
| | Ligand | Potential carcinogen based QSAR | Genotoxic carcinogenicity | Nongenotoxic carcinogenicity | Potential S. typhimurium mutagenicity |
| | Nova2 (9058064-6) | No | Negative | Negative | No | | Nova2 (95752-88-8) | No | Negative | Negative | No | | Nova2 (88765-82-6) | No | Negative | Negative | No | | Nova2 (Unique10) | No | Negative | Negative | No | | Nova2 (16876-27-0) | No | Negative | Negative | No | | Nova2 (513246-99-6) | No | Negative | Negative | No | | Nova2 (Unique80) | No | Negative | Negative | No | | Nova2 (279262-23-6) | No | Negative | Negative | No | | SAHA | No | Negative | Negative | No | | TSA | No | Positive | Negative | Yes |
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