Advances in Bioinformatics / 2014 / Article / Tab 8

Research Article

Utilization of Boron Compounds for the Modification of Suberoyl Anilide Hydroxamic Acid as Inhibitor of Histone Deacetylase Class II Homo sapiens

Table 8

Carcinogenicity and mutagenicity of the best ligands.

LigandPotential carcinogen based QSARGenotoxic carcinogenicityNongenotoxic carcinogenicityPotential S. typhimurium mutagenicity

Nova2 (9058064-6)NoNegativeNegativeNo
Nova2 (95752-88-8)NoNegativeNegativeNo
Nova2 (88765-82-6)NoNegativeNegativeNo
Nova2 (Unique10)NoNegativeNegativeNo
Nova2 (16876-27-0)NoNegativeNegativeNo
Nova2 (513246-99-6)NoNegativeNegativeNo
Nova2 (Unique80)NoNegativeNegativeNo
Nova2 (279262-23-6)NoNegativeNegativeNo
SAHANoNegativeNegativeNo
TSANoPositiveNegativeYes