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Advances in Bioinformatics
Volume 2014, Article ID 324753, 18 pages
Research Article

Alternate Phosphorylation/O-GlcNAc Modification on Human Insulin IRSs: A Road towards Impaired Insulin Signaling in Alzheimer and Diabetes

1Department of Chemistry, GC University Lahore, Lahore, Pakistan
2School of Biological Sciences, Goddard Building, The University of Queensland, Brisbane, QLD 4072, Australia

Received 24 August 2014; Accepted 10 November 2014; Published 17 December 2014

Academic Editor: Jian-Liang Li

Copyright © 2014 Zainab Jahangir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1 provides detailed analysis about experimental and predicted phosphorylation, kinases involved and surface accessibility for Ser/ Thr/ Tyr residues of human IRS-1.

  1. Supplementary Material