In Silico Screening of Mutated K-Ras Inhibitors from Malaysian Typhonium flagelliforme for Non-Small Cell Lung Cancer
Figure 3
Docked poses of the flagelliforme constituents to the binding pocket. K-ras PDB ID 4LYF. (a) Control ligand vinylsulphonamide docked in the switch II region. (b) Test ligands pheophorbide a (yellow), pheophorbide (blue), and pyropheophorbide a (magenta) bound at the SOS-interaction site while 1-hexadecene (green) and hexadecanoic acid (red) are bound in the switch II region.
