Identification of Novel Inhibitors for Tobacco Mosaic Virus Infection in Solanaceae Plants

Table 1

ADME prediction.

Property	Molecules						Limits
	Albendazole	Atropine	Isoproterenol	Riboflavin	Neomycin	Ampicillin
QP Polarizability	28.617 M	33.375 M	21.120 M	31.904 M	25.229 M	33.248 M	13.0/70.0
% Human Oral Absorption in GI (+−20%)	94	88	63	23	13	20	(<25% is poor)
Qual. Model for Human Oral Absorption	High	High	Medium	Low	Low	Low	(>80% is high)
QP for aqueous solubility	−4.456	−2.465	−0.842	0.915	1.427	−1.506	(−6.5/0.5)
QP log BB for brain/blood	−0.816	0.040	−0.828	−2.746	−2.505	−1.092	(−3.0/1.2)
QP hsa serum protein binding	0.221	0.122	−0.579	−2.435	−2.933	−0.936	(−1.5/1.5)
Lipinski rule of 5 violations	0	0	0	0	0	0	(Maximum is 4)
Jorgensen Rule of 3 violations	0	0	0	1	1	1	(Maximum is 3)