Research Article
Discovering Alzheimer Genetic Biomarkers Using Bayesian Networks
Table 1
The top candidate genes and the number of SNPs among each gene.
| | Gene | Chromosome | Number of SNPs | Potential pathways |
| | APOE | 19 | 6 | Cholesterol/lipid metabolism | | BIN1 | 2 | 101 | Endocytic pathways | | CLU | 8 | 32 | Immune and cholesterol/lipid metabolism | | ABCA7 | 19 | 36 | Cholesterol/lipid metabolism; immune and complement systems/inflammatory response | | CR1 | 1 | 71 | Immune and complement systems/inflammatory response | | PICALM | 11 | 138 | Endocytic pathways | | MS4A6A | 11 | 12 | Immune and complement systems/inflammatory response | | CD33 | 19 | 13 | Immune and complement systems/inflammatory response | | CD2AP | 6 | 61 | Endocytic pathways; immune and complement systems/inflammatory response |
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