Expressing Redundancy among Linear-Epitope Sequence Data Based on Residue-Level Physicochemical Similarity in the Context of Antigenic Cross-Reaction

Figure 2

Amino-acid residue substitution paths avoiding sterically incompatible changes (cf. (7)) for the 20 canonical proteinogenic residues. Numbers correspond to the subsets of stereochemically similar amino acids depicted in Figure 1. For every residue substitution along the paths shown, the number of unsatisfied hydrogen bonds is presented in Table 1.