Systematic Bioinformatic Approach for Prediction of Linear B-Cell Epitopes on Dengue E and prM Protein

Table 3

Overlapping epitopes on the E protein.

BepiPred	Ellipro	SVMTriP
^8SRDFVEGLSGATW^20; EP1/E	^16SGATWV^21⁢; EP2/E	NP
^63AKISNTTTDSRCPTQGEATLVEEQDAN^89; EP6/E	^62EAKISNTTTDSRCPTQGEATLVEEQDANFVCRRTFVDRGWGNGCGLFGKGSLITCAKFKCVT^123; EP5/E	NP
^97VDRGWGNGCGLF^108; EP7/E
^144HTGDQHQVGNESTEHGTTATITPQAPTTEIQLT^176; EP8/E	^165PQAPTTEIQLTDYGALTL^182; EP9/E	NP
^180ALTLDCSPRTGLD^192; EP10/E
^218LPWTSGASTSQETWNR^233; EP11/E	^223GASTSQETW^231; EP12/E	NP
^242TAHAKKQ^248; EP14/E	^237LVTFKTAHAKKQEVVVLGS^255; EP13/E	NP
^252VLGSQEGAMHTALTGATEIQTSGTTTI^278; EP15/E
^306FKLEKEVAETQHGT^319; EP18/E	^287LKMDKLTLKGMSYVMCTGSFKLEKEVA^313; EP17/E	^279FAGHLKCRLKMDKLTLKGMS^298; EP16/E
^326YEGTDAPCKIPFSTQDEKGVTQNGRLIT^353⁢; EP21/E	^322VQIKYEGTDAPCKIPFSTQDEKGVTQNG^349⁢; EP20/E	^310KEVAETQHGTVLVQIKYEGT^329; EP19/E
^356PIVTDKEKPVNIEAEPPFGES^376⁢; EP22/E	^356PIVTDKEKPV^365⁢; EP23/E	NP
^380IGVGEKA^386; EP25/E	^371PPFGESYIVIGVGEKALKLSWFKKGSSIGKMF^402; EP24/E
^393KKGSSIGKMFEATARGA^409; EP26/E
^417DTAWDFGSIGGVFT^430; EP28/E	^425IGGVFTSVGKLVHQIFGTAYG^445; EP29/E	^416GDTAWDFGSIGGVFTSVGKL^435; EP27/E
^469NSRSTSL^475; EP32/E	^454TMKIGIGVLLTWLGLNSRSTSLSMSCIAVGIITLY^488; EP30/E	^459IGVLLTWLGLNSRSTSLSM^478; EP31/E

NP: no prediction in the relevant region; bold italics indicates sequences that overlap between the predicted epitopes by three different tools.