Evaluation of Bioinformatic Programmes for the Analysis of Variants within Splice Site Consensus Regions

Figure 2

Splice site prediction relative to the position of mutations. (a) Sensitivity of splice site change detection relative to position; (b) % score change of the splice site caused by the mutations relative to position. In this calculation of sensitivity, mutations that were predicted to reduce splice site score compared to that of WT are considered positive.

(a)

(b)