Multiphase Simulated Annealing Based on Boltzmann and Bose-Einstein Distribution Applied to Protein Folding Problem

Algorithm 3

MQP pseudocode of MPSABBE algorithm.

(1) MQP Procedure( )

(2) Begin

(3) //Setting section

(4)   = Initial Temperature calculated by analytical method

(5)   = Initial value,

(6)    = initial value, = Initial value

(7) //Creation of initial solution

(8)   = Create the initial solution,

(9)  ,

(10)   Repeat //External Cycle

(11)   Repeat //Internal Cycle (Metropolis Cycle)

(12)     = Perturbation () //Uniform perturbation

(13)    Difference =

(14)    If Difference ≤ 0 Then

(15)      

(16)       

(17)    elseif Then //Boltzmann Probability

(18)      

(19)      

(20)    end if

(21)    If then //save

(22)      

(23)      

(24)    end if

(25)   Until Metropolis Cycle is Finished

(26)    =

(27)   If very close to 0 Then

(28)     = initial value

(29)   end if

(30)   

(31)  Until > //External Cycle

(32) End procedure