BacHbpred: Support Vector Machine Methods for the Prediction of Bacterial Hemoglobin-Like Proteins

Table 2

Performance of various SVM modules of HbL proteins domains classifications (flavoglobin, flavoglobin-cyto-FAD, flavoglobin-FAD, and single and trHb domain) developed using amino acid (AC), dipeptide composition (DC), PSSM, and MM profile, respectively.

HbL protein domain	Methods	ACC (%)	SN (%)	SP (%)	MCC	Parameters
						Flavoglobin (FAD-insignificant)	AC	91.88	65.62	92.69	0.74	50	200
DC	78.09	56.25	78.75	0.52	2		250
PSSM	84.05	78.13	84.23	0.77	2		400
MM	93.28	100.00	93.08	0.96	25		450
Hybrid	82.00	62.50	82.59	0.62	1		450
Flavoglobin-cyto-FAD/NAD	AC	89.65	99.51	75.89	0.86	10	200
	DC	87.78	98.55	72.77	0.83	5	200
	PSSM	91.04	100	78.57	0.89	2	500
	MM	89.17	96.96	78.34	0.84	25	400
	Hybrid	89.00	98.56	75.67	0.85	3	350
Flavoglobin-FAD	AC	83.68	50.00	84.71	0.53	10	275
	DC	77.05	59.37	77.60	0.54	1	275
	PSSM	82.74	18.75	84.71	0.09	1	500
	MM	89.74	50.00	90.96	0.60	15	500
	Hybrid	76.77	43.75	77.78	0.37	1	200
Single bac domain (globin-like)	AC	94.96	100	94.56	0.97	15	9
	DC	83.23	100	82.15	0.91	0.2	250
	PSSM	95.05	100	94.66	0.97	5	7
	MM	94.87	100	94.46	0.97	1	150
	Hybrid	91.51	100	90.83	0.95	0.1	350
Truncated BacHb domain (globin_trunc_bac-like)	AC	85.26	98.89	80.62	0.89	5	350
	DC	78.17	98.89	71.13	0.83	1	275
	PSSM	87.97	100	83.88	0.92	1	400
	MM	85.07	99.26	80.25	0.89	4	500
	Hybrid	80.03	100	73.25	0.85	1	150