Structural Dynamics of Human Argonaute2 and Its Interaction with siRNAs Designed to Target Mutant tdp43

Table 1

List of rationally designed and experimentally proven (superscripted) siRNAs (having 21 nucleotides) used in this study.

S. number	siRNA	Sequences	GC content in %
1	128	UGAGACACUGGAUUCCUGUUU	43
2	251	UGGAUGAGACAGAUGCUUCUU	43
3	341	CAACCGAACAGGACCUGAAUU	48
4	383	ACCAUAAGAACUUCUCCAAUU	33
5	537	UCAUCUUGGCUUUGCUUAGAA	38
6	1113	CUCUUAUAGUGGCUCUGACUU	43
7	1115	UUAGAGCCACUAUAAGAGUUU	33
8	ICAM2	CUCUAUAACCGCCAGCGGAUU	52
9	GRK	AACUGCCUGAAGAGACGUCUU	48