Random versus Deterministic Descent in RNA Energy Landscape Analysis

Table 6

Run-time in minutes of RNAsubopt, Barriers, and modified RNAlocmin descent procedures for conformations. Note: RNAlocmin energy evaluation using energy_of_move().

Number			RNAsubopt time	Barriers time	Gradient time	Random time	First time
1	99	1.0	1.48	6.43	5.42	4.03	3.40
2	99	1.0	1.40	5.78	3.03	3.67	3.62
3	113	2.0	1.48	13.63	3.95	6.68	3.38
4	124	1.0	1.70	10.52	3.62	3.27	3.12
5	284	1.5	5.87	18.52	7.22	6.45	6.18
6	302	1.5	6.58	33.90	7.12	6.04	5.93
7	386	2.5	9.25	60.12	12.67	11.10	10.57
8	400	1.5	10.25	53.30	6.62	5.82	5.27
9	407	1.0	15.12	40.12	5.18	4.15	3.95
10	504	2.0	15.75	47.63	9.10	8.40	7.92
Total			68.88	289.84	63.94	59.61	53.34