In Silico Screening of Aptamers Configuration against Hepatitis B Surface Antigen

Figure 3

Graphical representation of HBsAg RMSD backbone for 20 ns (a) and fluctuations of HBsAg backbone (RMSF) for 20 ns (b). HBsAg was stable after 3-4 ns simulation, and the highly movable residues were locating near 50 a.a and in “a” determinant region (99-150 a.a).

(a)

(b)