Research Article

In Silico Screening of Aptamers Configuration against Hepatitis B Surface Antigen

Table 1

Short single-strand DNA (ssDNA) aptamers sequence obtained based on the loop and hairpin structure available from each H01, H02, and H03.

No.Aptamer nameAptamer originalSequence (5′-3′)

1H01aH01-CCACAGCGAACAGCGCGGCAGG-
2H01bH01-GCGGGACATAATAGTGCTTACTACGACCTGC-
3H02aH02-GGGAATTCGAGCTCGGTACCC-
4H02bH02-ATGAAGTATTATTACCCAAT-
5H03aH03-GCTCGCTGCAGGCATGCAAGC-

The bold and underlined alphabets were the sequences selected to design the three-dimensional conformation based on the hairpin formed in the two-dimensional structure.