Table 3: Number of atoms in each aptamer, Vina docking score, and Root Mean Square (RMS) value of each docked aptamer before and after docking on HBsAg. The RMS value of each aptamer was determined by aligning before and after docking structure using PyMOL.

No.Aptamer nameNo. of atomsRMS of initial and after docking structuresVina score (kJ/mol)

1H01a2226.978-27.196
2H01b2548.944-31.798
3H02a2548.006-24.686
4H02b2566.549-24.686
5H03a2556.133-22.175